vim, 263 bytes

Result

WA

Duration

516ms

Code [DL]

:let l=[]
:for i in range(4)
for c in split(getline(i+1),'\_s')
call add(l,str2nr(c))
endfor
endfor
:for i in range(9)
let l[i+3]-=l[i%3]
endfor
:call setline(1, (l[3]*l[7]*l[11]+l[6]*l[10]*l[5]+l[9]*l[4]*l[8]-l[5]*l[7]*l[9]-l[8]*l[10]*l[3]-l[11]*l[4]*l[6])/6)
ZZ

Disassembly

:let l=[]<NL>:for i in range(4)<NL>for c in split(getline(i+1),'\_s')<NL>call add(l,str2nr(c))<NL>endfor<NL>endfor<NL>:for i in range(9)<NL>let l[i+3]-=l[i%3]<NL>endfor<NL>:call setline(1, (l[3]*l[7]*l[11]+l[6]*l[10]*l[5]+l[9]*l[4]*l[8]-l[5]*l[7]*l[9]-l[8]*l[10]*l[3]-l[11]*l[4]*l[6])/6)<NL>ZZ

stdin

50 89 01
04 03 25
40 41 10
72 34 46

stdout

stderr

strace